Volcano Plot

A volcano plot is a type of scatter plot, used to identify significant fold changes in probes.  It has the significance on the vertical axis and the fold values on the horizontal axis. 

For bivariate data (case/control, male/female, treatment/placebo etc), each probe is represented by one point, the Y value being its adjusted significance and the X value being the fold change.

For multivariate data (dose1/dose2/dose3/no dose for instance, or child / adolescent / adult), each probe is represented by as many values as there are groups.  The Y values are all the same, being the significance.  The X values are the group scores relative to the average of all scores.

The probes can be selected.

bivariate volcano
MV volcano
Bi-variate data
Multi-variate data

See Also

Volcano plot (Wikipedia)

Differential Analysis

Help Front Page